A Heart-Lung Transplantation Marks a New Era – for Patient and Hospital

3D Illustration of Human Body Organs (Lungs with Heart Anatomy)Building on pioneering work performed during the first wave of heart-lung transplantation, Brigham and Women’s Hospital has resumed its heart-lung program and is once again performing the rare procedure.

Read More

Could a Cancer Protein Be a Target for Preventing Lung Vessel Scarring?

PET imaging of research

Although there is no cure for pulmonary arterial hypertension (PAH), investigators from Brigham and Women’s Hospital are unraveling the molecular mechanisms that may control PAH’s development and progression in an effort toward finding treatments that could halt its advancement. In Science Translational Medicine, researchers shared results from a study that identifies the cancer protein NEDD9 as a critical player in disease development, with potential therapeutic implications for patients with PAH.

Read More

Moving Toward “Virtual Biopsy” of Gliomas Using Artificial Intelligence

MRI showing glioma

What if you could know, from a pre-operative MRI, whether a glioma was likely to have a genetic mutation that significantly alters prognosis?

Read More

A Deeper Look at Severe Asthma Yields NET Results

Neutrophil cell (white blood cell) in blood smear, analyze by microscope

A study by investigators at Brigham and Women’s Hospital that models allergic lung inflammation provides new insight into how neutrophil cytoplasts can contribute to asthma severity. The results may have implications for developing drugs for people with severe asthma.

Read More

When is the Best Time to Measure Glucose During Total Joint Arthroplasty?

Study explores the optimal time to measure glucose levels after TJA

Mid section of doctor examining patient knee in clinic

A periprosthetic joint infection (PJI) after total joint arthroplasty (TJA) is often a devastating experience for a patient, involving a long treatment process that dramatically reduces a patient’s quality of life.

Read More

“Prehab” Program Lowers Length of Hospital Stay by 12 Hours

Closeup shot of an unrecognizable physiotherapist treating a patientFive years ago, Wolfgang Fitz, MD, a knee replacement surgeon in the Department of Orthopaedic Surgery, asked his patients to bridge the two-to-three months prior to surgery with physical conditioning, tailored to their activity levels and knee osteoarthritis.

Read More

Health Coaching and Financial Incentives Boost Physical Activity After Total Knee Replacement

There’s a growing interest in finding strategies to increase physical activity in patients who have undergone total knee replacement (TKR). In a clinical trial, Brigham and Women’s Hospital researcher, Elena Losina, PhD, and colleagues showed that one-on-one health coaching and financial incentives substantially increased physical activity in patients following TKR. The results were published in the April 2018 issue of Arthritis Care & Research.

Pair of legs walking on a trail in nature towards the light

Read More

Strengthening the Role of Psychiatry in Medicine

Dr. Gitlin and fellow in a medical unit

Consultation-Liaison (C-L) Psychiatry has been an important component of psychiatry for over 70 years and a certified subspecialty under the American Board of Medical Specialties since 2004. Brigham and Women’s Hospital has one of the largest C-L divisions and one of the largest C-L fellowship programs in the country, with a mission to maintain strong bonds between psychiatry and other specialties of medicine.

Read More

Expanding the Frontiers of Breast Cancer Immunotherapy

Pipette dropping stem cell research fluid on pcr plate. Medical Dropper

Elizabeth A. Mittendorf, MD, PhD, a breast cancer surgeon and international leader in breast cancer vaccines, recently joined Brigham and Women’s Hospital (BWH) from the MD Anderson Cancer Center in Houston, where her research focused on vaccines that target the HER2 protein expressed on many breast tumors. At the Brigham, her work focuses on advancing our understanding of breast cancer immunotherapies.

Read More

Focused Ultrasound: Noninvasive Surgery Stops Tremor in its Tracks

Image courtesy of INSIGHTEC

Each week, two or three patients with medically refractive essential tremor undergo  MRI-Guided Focused Ultrasound (MRgFUS) Thalamotomy at Brigham and Women’s Hospital, with often-life-changing results – fulfilling the promise of a technology that dawned here 20 years ago.

Read More