New Clues in Predicting Spontaneous Preterm Birth and Preeclampsia

A pregnant Caucasian woman is indoors in a doctor's office. Her female doctor is wearing medical clothing. The woman is holding her stomach which the doctor writes on a clipboard.Seven to eight percent of pregnancies end in spontaneous preterm birth. About five percent of pregnancies involve preeclampsia. The problem is, we do not do a good job predicting which women are at heightened risk for these issues.
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Could ‘Precursor Escape’ Explain Advanced High-Grade Serous Carcinoma?

Over a decade ago, Christopher Crum, MD, helped design the protocol that revealed the fallopian tubes to be the origin of most high-grade serous carcinomas (HGSCs), the tumor type afflicting over two-thirds of women with ovarian cancer.

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Unlocking the Mysteries Behind Uterine Fibroids

3D rendering of DNA double helix on a blue background.Uterine leiomyomatas, also known as uterine fibroids, are the most common pelvic tumor in women. About 75 percent of women will develop fibroids, and the average affected uterus has six to seven of these tumors. Cynthia Morton, PhD, at Brigham and Women’s Hospital is active in studying gene variants that cause fibroid tumors and can influence risk as well.

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Zeroing in on the Genetic Roots of Fibroids

Cynthia Morton, PhD

In the effort to identify genetic drivers of fibroids, the lab of Cynthia Morton, PhD, at Brigham and Women’s Hospital (BWH) is at an international crossroads. In recent years, Morton and investigators worldwide have been studying the molecular and genetic background of fibroids that may contribute to their development and growth.

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Placenta Accreta on the Rise, Research Suggests More Options for Safe Management

 

The increasing frequency of placenta accreta is raising new questions about the best way to manage this dangerous condition. At Brigham and Women’s Hospital researchers are creating a body of data to learn if some women with previa-accreta can be selected for a later delivery, if placenta accreta requires general anesthesia, and potential future risks for women who have had accreta during pregnancy.

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Research Offers Insight into Option for Vaginal Versus Cesarean Delivery for Twins

In the face of rising Cesarean section rates – including nearly all twin births, obstetrician Daniela Anne Carusi, MD, MSc, and colleagues at Brigham and Women’s Hospital (BWH) questioned whether Cesarean delivery was warranted for all twins.

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Infant Brain Monitoring Brings NICU Care to New Level

In the newly expanded NICU at Brigham and Women’s Hospital (BWH), advanced monitoring of newborn brain activity and oxygen saturation in the brain tissue provides optimal care and protection.

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Brigham and Women’s Hospital Completes Expansion of Patient-focused Level 3 NICU

We are pleased to announce the completed expansion and renovation of the Newborn Intensive Care Unit at Brigham and Women’s Hospital. This regional Level 3 NICU, and the largest NICU in Massachusetts, is a state-of-the-art facility with a design that reflects evidence-based research about the optimal environment for critically ill infants and their families.

 

Disparities in Care for Publicly Insured Women with Pregestational Diabetes

A Brigham and Women’s Hospital study examines the association among public health insurance, preconception care, and pregnancy outcomes in pregnant women with pregestational diabetes.  Read More

Early Diagnosis of Ovarian Cancer via a Blood Test, Aided by Artificial Intelligence

With the help of artificial intelligence, researchers from Brigham and Women’s Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) have developed an early diagnostic tool for ovarian cancer that shows equal sensitivity but far fewer false positives than previous testing strategies. Read More