Harnessing Ultrasound to Deliver RNA-based Therapies into Gut Cells

While biologic drugs hold enormous promise for treating a wide range of gastrointestinal disorders, delivering these large molecules into the GI tract is formidable. To address this challenge, Brigham and Women’s Hospital (BWH) researcher C. Giovanni Traverso, MB, BChir, PhD, and colleagues have developed an ultrasound method for delivering drugs and macromolecules into the gut. Read More

Brigham and Women’s Mastocytosis Center Offers Advanced Approaches to Diagnosis and Treatment

Specialists in the Mastocytosis Center have developed advanced approaches for evaluating and treating mast cell disease, including state-of-the-art techniques to accurately diagnose the disease. Read More

Wireless Power Can Drive Tiny Electronic Devices in the GI Tract

Imagers, gastric pacemakers and other diagnostic and therapeutic tools could someday transform the way diseases of the gastrointestinal tract are measured and treated. But in order for these electronic devices to work, they need a power source. Traditional power sources, such as batteries, can be incompatible with the mucosal lining of the gastrointestinal tract and have a limited lifespan within the body. A more promising possibility is to power electronic devices from outside the body or potentially by the body. Read More