Connective Tissue Disorders Program Provides Comprehensive Care

Male cardiologist gestures while discussing diagnosis with an unrecognizable female patient.For more than two decades, Brigham Health has been providing comprehensive cardiac care for patients with Marfan syndrome and other connective tissue disorders, including Loeys-Dietz syndrome and Ehlers-Danlos syndrome.

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Q&A with William Sauer, MD: New Chief of Brigham’s Cardiac Arrhythmia Service

Stethoscope and ElectrocardiogramWilliam Henry Sauer, MD, the new chief of the Cardiac Arrhythmia Service at Brigham Health, discusses his vision for the department and how an expert team of electrophysiologists are providing leading-edge care for abnormal heart rhythms that affect a variety of patients, particularly those with complex medical concerns.
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Novel SEQaBOO Study of Newborn Hearing Loss Foretells Role for Obstetricians in Genomic Medicine

The ear of a newborn baby only a few weeks old.As genetic and genomic sequencing become incorporated into newborn screening for hearing loss, patients may look to obstetricians for guidance on genetic testing decisions.

Auditory screening of newborns, mandated by most states in recent decades, now reaches an estimated 98 percent of newborns in the United States and has significantly reduced the average age for identifying congenital deafness. But adding genetic testing could drive more accurate diagnosis and personalized management during infancy’s critical window when the brain’s speech and language center is developing rapidly.
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Creating Healthy Families, One Embryo at a Time

embryo in a petri dishPredicting which IVF embryos are most likely to produce a healthy pregnancy is an ongoing challenge in the field. For embryologist Catherine Racowsky, PhD, it is a theme across her varied work as director of the IVF Lab at Brigham and Women’s Hospital, as a researcher of new techniques to find the healthiest embryos and as incoming president of the American Society of Reproductive Medicine.

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Stratifying Accreta Risks Before Labor to Improve Maternal Health

In the Hospital, Close-up Shot of the Doctor Doing Ultrasound / Sonogram Scan to a Pregnant Woman. Obstetrician Moving Transducer on the Belly of the Future Mother.With placenta accreta contributing to rising rates of severe maternal morbidity nationwide, the Program for Surgical Obstetrics and Placental Abnormalities at Brigham and Women’s Hospital is zeroing in on antepartum risk stratification as a tool for preserving maternal health.
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Improving Survival Benefit in Glioblastoma Patients with Neoadjuvant Immunotherapy

MR images of a brain at baseline vs. ONC201A new study featured on the cover of the March issue of Nature Medicine offers hope for treating patients with glioblastoma. In a small randomized controlled clinical trial, patients with recurrent glioblastoma lived nearly twice as long if they received an immunotherapy drug prior to and following surgery, compared to patients who only received the drug after surgery.
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MR-Guided Radiation Therapy: A More Precise Way to See, Track and Treat Tumors

New MR-Imaging (Left) – Traditional Cone-beam CT (Right)
New MR-Imaging (Left) – Traditional Cone-beam CT (Right)

For the first time, cancer patients in New England will have a cutting-edge option for radiation treatment of soft-tissue tumors. The new MR-Guided Radiation Therapy (MR-RT) treatment at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), launching this summer, will give physicians real-time, pinpoint accuracy for radiation planning and treatment.
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New Hope for Late-Stage Endometrial Cancer Patients

drawing of DNA double helix with the phrase Novel therapies in Endometrial CancerWhen diagnosed and treated in its early stages, endometrial cancer is largely curable. However, for the 10 to 15 percent of patients diagnosed with late-stage disease, standard therapy does not lead to a cure.
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Can Your Patient’s Smartphone Signal Early GBM Recurrence?

cartoon of a smartphone and a map of a human brainWhen following a patient for brain tumor recurrence, standard assessments fall short:  Imaging and clinical exams each occur only a few times per year, and patient questionnaires capture only a moment in time and may be unreliable due to the challenge of accurate self-assessment amidst insidious decline.
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Expanded Autonomic Testing Helps to Pinpoint Causes of Orthostatic Intolerance

drawing of a tilt tableUsing expanded, state-of-the-art capabilities in autonomic testing, Peter Novak, MD, PhD, chief of the Division of Autonomic Neurology at Brigham and Women’s Hospital, is driving better understanding of hard-to-diagnose patients with orthostatic intolerance.
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